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Frequently Asked Questions About Opill® and Contraception Access

What is Opill®?

What is Opill®?
Opill® is a progestin-only pill (POP) and is estrogen free. It contains a synthetic version of the naturally produced hormone progesterone. It is a convenient, daily over-the-counter birth control pill that you use every day to prevent pregnancy. The best part is you don't need a prescription from your doctor to purchase it! It's been approved by the FDA as a non-prescription daily oral birth control pill.

How does Opill® work?
Opill® works by thickening the cervical mucus, which helps block sperm from reaching the egg and by preventing the ovaries from releasing eggs in some cycles.

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References

[1] U.S. Food and Drug Administration. (2023, July 14). Opill (0.075mg Oral Norgestrel Tablet) Information. https://www.fda.gov/drugs/postmarket-drug-safety-information-patients-andproviders/opill-0075mg-oral-norgestrel-tablet-information

[2] Worly BL, Gur TL, Schaffir J. The relationship between progestin hormonal contraception and depression: a systematic review. Contraception. 2018 Jun;97(6):478-489. doi: 10.1016/j.contraception.2018.01.010. Epub 2018 Feb 26. PMID: 29496297.

[3] Lee IT, Barnhart KT. What Is an Ectopic Pregnancy? JAMA. 2023;329(5):434. doi:10.1001/jama.2022.22941

[4] Planned Parenthood. What is ectopic pregnancy?: Definition and treatment. Ectopic Pregnancy.Retrieved November 17, 2023, from https://www.plannedparenthood.org/learn/pregnancy/ectopic-pregnancy.

[5] Lopez LM, Ramesh S, Chen M, Edelman A, Otterness C, Trussell J, Helmerhorst FM. Progestin-only contraceptives: effects on weight. Cochrane Database Syst Rev. 2016 Aug 28;2016(8):CD008815. doi:10.1002/14651858.CD008815.pub4. PMID: 27567593; PMCID: PMC5034734.

[6] Graham CA, Ramos R, Bancroft J, Maglaya C, Farley TM. The effects of steroidal contraceptives on the well-being and sexuality of women: a double-blind, placebo-controlled, two-centre study of combined and progestogen-only methods. Contraception. 1995 Dec;52(6):363-9. doi:10.1016/0010-7824(95)00226-x. PMID: 8749600.

[7] Curtis KM et al. U.S. Medical Eligibility Criteria for Contraceptive Use, 2016. MMWR Recomm Rep 2016;65(No. RR-3):1–104. DOI: http://dx.doi.org/10.15585/mmwr.rr6503a1Curtis KM et al. U.S. Medical Eligibility Criteria for Contraceptive Use, 2016. MMWR Recomm Rep 2016;65(No. RR-3):1–104. doi:http://dx.doi.org/10.15585/mmwr.rr6503a1-8-